Maintaining a Ford (or Chevy) can be rather easy. Most any place can do it, for one thing, so you don't really have to plan out the routine maintenance. For a Sprinter, for the things you don't do yourself (like filters and oil changes) you must plan them out to have them done by a Sprinter tech, usually (but not always) at a Sprinter or former Sprinter dealer.
Because Dodge dealers are no longer Sprinter dealers, the Sprinter parts at a Dodge dealer can often be higher than at a Mercedes or Freightliner dealer because the Dodge dealers are getting hosed on their prices. Often it's cheaper to buy your own parts online and then have the dealer install them for you. A fuel filter costs about $35 if you buy it yourself, and it takes about 10 minutes to change with a long handled screw driver and a socket wrench with a Torx bit. Have a dealer do it and it's $100.
But the main things about maintaining a Sprinter are two things, one is to stick to the maintenance schedule, absolutely, and the other is to use only fluids approved by Mercedes. The common sense notion of substituting Lucas or some other thing for a quart or two of oil after a certain number of miles may make sense in some trucks and vans, but it'll cause problems in a Sprinter. With a Ford, for the most part 30 weight oil is 30 weight oil, and any ol' oil will do. With a Sprinter, if it ain't on The List, don't put it in there. You can't just pull into Quickie Lube-It-Up and change the oil using whatever oil du jour they've got on special. The wrong transmission fluid will get you a brand new transmission, and it'll get you one right quick. The wrong engine coolant will get you a new water pump and heater core. If it says "For use in all aluminum engines" on the label, it's probably not for use in a Sprinter even though a Sprinter's engine is aluminum.
Learn the maintenance schedule and which approved fluids can be used, and don't deviate from that at all. Those who deviate from it find their Sprinter to be a POS with nothing but maintenance problems. It's a different mindset, and it takes a considerable amount of time to learn all the differences.