A good starting point would be to PM (private message) member Nightcreacher (aka Steve) who drives a "E" for the Fed. I believe he could fill you in as he has done different trailers and ran both solo & teams.
It all depends do you own the truck? TT owners doing very well at FedEx Custom Critical run team. Steve can help you the best like Davekc said. FedEx Custom Critical asks that you have Haz mat and be able to go to Canada. What kind of Trailer will you be pulling?